Multiscale Modeling and Simulations of Biological Systems

SpeakerGeorge Em Karniadakis

  Division of Applied Mathematics, Brown University

  & Department of Mechanical Engineering, MIT

&Collaboratory on Mathematics for Mesoscopic Modeling of Materials, PPNL

Title: Multiscale Modeling and Simulations of Biological Systems

Date & Time: 11:15-12:15, Dec.19,2016

LocationM842, Lecture Hall, Beijing Institute for Scientific and Engineering Computing, 8th Floor, Scientific Research Building

Abstract: A new approach to multiscale modeling of arterial trees and vascular pathologies will be presented using hybrid methods based on the coupling of Navier-Stokes and elasticity equations with the dissipative particle dynamics (DPD) method, which is a coarse-grained version of molecular dynamics (MD) allowing simulations on larger domains and longer time scales than MD. Domain decomposition algorithms interfacing DPD with MD and the continuum Navier-Stokes equations will also be presented. Examples will includemodeling of full simulation of arterial trees, blood disorders such as malaria and sickle cell anemia, and a large-scale multiscale simulations of brain aneurysms (see figure).